At some point while viewing samples this caught my eye. I have had discussions trying to explain what this could be. The only vague preliminary suggestion we could even begin to think of was not a very useful one at this stage. We discussed the vague possibility that maybe some sort of energy was being absorbed by the lipids which was wanted to gather small sized materials or particles in order to expand its mass. While doing so it would run short of the material to keep up with the expanse process and collapse. Just a vague and pretty much useless theory at this point. But certainly something to keep an eye on. Enjoy the movie !
Thanks in advance for any help through KO-FI.
Karl: I have no idea what kind of sample prep / handling is involved with these images. Is a cover slip used? Is there fluid extruding beyond cover slip thats exposed to drying? Has your mike been "on" for a while which warms it and the sample on the slide? What this looks like to me is water vapor condensing on the underside of the cover slip, and when large enough to touch the bottom surface, the drop gets sucked down. They "grow" and then suddenly "shrink", typical of condensation drops. I recommend using a large cover slip for every sample, which reduces drying from edge. Gently allow the cover slip to drop down onto sample using a needle or similar probe to minimize bubbles getting trapped. Also, keep them cool. Warming the slide in itself causes fluids to move / stream towards edges. This also causes clumping of RBCs. Uniform sample handling is all important here!
My intent is to get involved much as I can help out. Time is of essence. Would like to correspond w/Ana but no luck in that dept. However, when I became "paid" member of her stack, I got a tiny allotment of "contact" with her. This is where the topic of birefringence suddenly came from. She is using dark field which is all reflected light, like birefringence. But, now I learn the micro dots might be florescent so can produce own light. I am convinced their movement is by Brownian motion. The jerky movement is typical of motion induced by molecular vibration. Cooling the sample should slow it down (temp dependent).
FYI: my Leitz scope is currently sent off for thorough cleaning and alignment. My father used it in his late years and some things need repair. I was offered a nice Leitz Pol scope for reasonable that I might pick up. I only have 3 scopes, so whats one more - lol. My optics are good but not new. It's all either Leitz or Zeiss, but I dont have the newer plan objectives, phase contrast, etc. I'm aware Ana has had trouble with her scope. Would like to see her trade up to a top of line Leica with all bells and whistles, but they run about 100k depending on whats included. Maybe we can garner funding to make it happen. Dont know if she has interest, but she might also want to get a good used SEM to be able to see the micro-dots. I have the same goal, but dont know how far I'll get using Pol scope and geological embedding and sectioning techniques, if I can get some of them concentrated for embedding. Those things are so small I dont know if I can get a few of them sliced open within the embedding epoxy. One more swipe even with super fine grit grinding compound will probably just grind out the whole thing - dont know. This is the wrong technique for something that small, but I'll try. This is why I suggest an SEM. I used one back in grad school, but the one I used is likely a museum piece now. Wouldn't mind being involved with that if it comes to it.
In terms of somehow making progress against mRNA, thats a tall order but I'll do what I can to contribute. I sense a large part of this battle is against inanimate materials - the micro dots and the rubber strand formation. I used to do blood electrification, but now dont dare as the strands grow faster under voltage. FYI, this process uses low voltage on skin over blood vessels to kill off parasites bacteria and viruses in blood. This very useful tool is now out the window. What next I dont know. Ana is on track using EDTA etc, but this is also rough on body as I understand. However, the plant world is full of enzymes we haven't tried yet. Some might be better than EDTA. I dont have a lab available here so cant really help outside of making suggestions. I'm experienced in wet soil chemistry, which is complex soup of redox reactions. I'm hoping this knowledge might be useful in deterring strand formation. I think strand formation involves electromagnetic charges that attract material in the growth process. We need to turn this off, or make use of it for filtration.